Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine.

@article{Aittoniemi2007InsightIT,
  title={Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine.},
  author={Jussi Aittoniemi and Perttu S. Niemel{\"a} and Marja T. Hyv{\"o}nen and Mikko Karttunen and Ilpo Vattulainen},
  journal={Biophysical journal},
  year={2007},
  volume={92 4},
  pages={1125-37}
}
The effects of cholesterol (Chol) on phospholipid bilayers include ordering of the fatty acyl chains, condensing of the lipids in the bilayer plane, and promotion of the liquid-ordered phase. These effects depend on the type of phospholipids in the bilayer and are determined by the nature of the underlying molecular interactions. As for Chol, it has been shown to interact more favorably with sphingomyelin than with most phosphatidylcholines, which in given circumstances leads to formation of… CONTINUE READING
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