Insight Into Parkinson’s Disease: Does α-Synuclein Use the MVB/Endocytosis Pathway as a Route for Degradation in the Lysosome?

  • Alexandra Ayala
  • Published 2010


Parkinson’s disease is a fatal and incurable human neurodegenerative disorder that destroys midbrain neurons. The misfolding, accumulation, and aggregation of the protein α-synuclein is thought to kill these cells. Enhancing α-synuclein degradation may help prevent its accumulation and aggregation, while protecting cells against toxicity. For this thesis… (More)


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