Insertion with long target duplication: a mechanism for gene mobility suggested from comparison of two related bacterial genomes.

@article{Nobusato2000InsertionWL,
  title={Insertion with long target duplication: a mechanism for gene mobility suggested from comparison of two related bacterial genomes.},
  author={Ayaka Nobusato and Ikuo Uchiyama and Seishi Ohashi and Ichizo Kobayashi},
  journal={Gene},
  year={2000},
  volume={259 1-2},
  pages={99-108}
}
The complete genome sequences of two closely related organisms--two Helicobacter pylori strains--have recently become available. Comparison of these genomes at single base pair level has suggested the presence of a mechanism for bacterial gene mobility--insertion with long target duplications. This mechanism is formally similar to classical transposon insertion, but the duplication is much longer, often in the range of 100bp. Restriction and/or modification enzyme genes are often within or… CONTINUE READING