Insertion sequences shared by Bordetella species and implications for the biological diagnosis of pertussis syndrome

@article{Tizolova2012InsertionSS,
  title={Insertion sequences shared by Bordetella species and implications for the biological diagnosis of pertussis syndrome},
  author={Anette Tizolova and Nicole Guiso and S. Segado Guillot},
  journal={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2012},
  volume={32},
  pages={89-96}
}
The molecular diagnosis of pertussis and parapertussis syndromes is based on the detection of insertion sequences (IS) 481 and 1001, respectively. However, these IS are also detected in the genomes of various Bordetella species, such that they are not specific for either B. pertussis or B. parapertussis. Therefore, we screened the genome of recently circulating isolates of Bordetella species to compare the prevalence of IS481, IS1001 and, also IS1002 with previously published data and to… CONTINUE READING
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