Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complex.

@article{Stuart2002InsertionOP,
  title={Insertion of proteins into the inner membrane of mitochondria: the role of the Oxa1 complex.},
  author={Rosemary A. Stuart},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1592 1},
  pages={79-87}
}
The inner mitochondrial membrane harbors a large number of proteins that display a wide range of topological arrangements. The majority of these proteins are encoded in the cell's nucleus, but a few polytopic proteins, all subunits of respiratory chain complexes are encoded by the mitochondrial genome. A number of distinct sorting mechanisms exist to direct these proteins into the mitochondrial inner membrane. One of these pathways involves the export of proteins from the matrix into the inner… CONTINUE READING

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