Insertion of peptide chains into lipid membranes: An off‐lattice Monte Carlo dynamics model

@article{Milik1993InsertionOP,
  title={Insertion of peptide chains into lipid membranes: An off‐lattice Monte Carlo dynamics model},
  author={M. Milik and J. Skolnick},
  journal={Proteins: Structure},
  year={1993},
  volume={15}
}
  • M. Milik, J. Skolnick
  • Published 1993
  • Chemistry, Medicine
  • Proteins: Structure
  • A combination of dynamic Monte Carlo simulation techniques with a hydropathy scale method for the prediction of the location of transmembrane fragments in membrane proteins is described. The new hydropathy scale proposed here is based on experimental data for the interactions of tripeptides with phospholipid membranes (Jacobs, R.E., White, S.H. Biochemistry 26:6127–6134, 1987) and the self‐solvation effect in protein systems (Roseman, M.A., J. Mol. Biol. 200:513–522, 1988). The simulations give… CONTINUE READING

    Topics from this paper.

    Membrane protein folding and stability: physical principles.
    • 1,498
    • PDF
    Effective energy function for proteins in lipid membranes
    • 212
    Interactions of hydrophobic peptides with lipid bilayers: Monte Carlo simulations with M2delta.
    • 42
    • Highly Influenced
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 39 REFERENCES
    Helix geometry in proteins.
    • 854
    The actions of melittin on membranes.
    • 658
    The structure of melittin in membranes.
    • 254