Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle.

@article{Gigure2004InsertionOH,
  title={Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle.},
  author={J F Gigu{\`e}re and Salim Bounou and J. S. Paquette and Joaqu{\'i}n Madrenas and Michel J Tremblay},
  journal={Journal of virology},
  year={2004},
  volume={78 12},
  pages={6222-32}
}
Human immunodeficiency virus type 1 (HIV-1) carries virus-encoded and host-derived proteins. Recent advances in the functional characterization of host molecules inserted into mature virus particles have revealed that HIV-1 biology is influenced by the acquisition of host cell membrane components. The CD28/B7 receptor/ligand system is considered one of the fundamental elements of the normal immune response. Two major cell types that harbor HIV-1 in vivo, i.e., monocytes/macrophages and CD4+ T… CONTINUE READING
7 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…