Insertion of dominant selectable markers into the human genome

@article{Housman1987InsertionOD,
  title={Insertion of dominant selectable markers into the human genome},
  author={David E. Housman},
  journal={Somatic Cell and Molecular Genetics},
  year={1987},
  volume={13},
  pages={441-446}
}
Summary and conclusionsIn the above discussion, I have outlined the current status of our efforts to use retroviral vectors to introduce selectable markers into the human genome and to use these markers for mapping specific chromosomal regions. I have not reviewed in detail the extensive characterization of the mouse H-2 region carried out by David Nelson and John Weis based on the insertion of a single retroviral element. This analysis has provided a model for the application of retroviral… CONTINUE READING
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