Insertion Sequence–Driven Diversification Creates a Globally Dispersed Emerging Multiresistant Subspecies of E. faecium

@article{Leavis2007InsertionSD,
  title={Insertion Sequence–Driven Diversification Creates a Globally Dispersed Emerging Multiresistant Subspecies of E. faecium},
  author={Helen L. Leavis and Rob J. L. Willems and Willem J. B. van Wamel and Frank H. J. Schuren and Martien P. M. Caspers and Marc Bonten},
  journal={PLoS Pathogens},
  year={2007},
  volume={3},
  pages={470 - 485}
}
Enterococcus faecium, an ubiquous colonizer of humans and animals, has evolved in the last 15 years from an avirulent commensal to the third most frequently isolated nosocomial pathogen among intensive care unit patients in the United States. E. faecium combines multidrug resistance with the potential of horizontal resistance gene transfer to even more pathogenic bacteria. Little is known about the evolution and virulence of E. faecium, and genomic studies are hampered by the absence of a… CONTINUE READING
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