Insertion (21;8)(q22;q22q22): A masked type t(8;21) in a patient with acute myeloid leukemia


A 43-year-old man was diagnosed with AML with cellular maturation (AML-M2) according to the French-American-British classification criteria. A cytogenetic study with a G-banding method was initially reported as 45,X,-Y. However, dual-color, dual-fusion fluorescence in situ hybridization (FISH) with probes for the AML1 and the ETO genes showed an unusual… (More)


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