Insecticide Resistance on the Move

  title={Insecticide Resistance on the Move},
  author={Ian Denholm and Gregor J. Devine and Martin S Williamson},
  pages={2222 - 2223}
Understanding the genetics of insecticide resistance is critical to the prediction and management of resistant insects. In their perspective, [Denholm][1] and colleagues describe new work on the genetics of DDT resistance in Drosophila ([Daborn][2] et al .). The data reinforce the hypothesis that resistance can spread quickly to new areas through migration of resistant insects. [1]: [2]:… Expand
Origin, selection, and spread of diamide insecticide resistance allele in field populations of diamondback moth in east and southeast Asia.
The information of the present study is useful to monitor resistance using molecular markers and to develop strategies to delay the evolution of diamide resistance. Expand
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Identification, Validation, and Application of Molecular Diagnostics for Insecticide Resistance in Malaria Vectors.
Insecticide resistance is a major obstacle to control of Anopheles malaria mosquitoes in sub-Saharan Africa and requires an improved understanding of the underlying mechanisms. Efforts to discoverExpand
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Insecticide Resistance Mechanisms in the Green Peach Aphid Myzus persicae (Hemiptera: Aphididae) II: Costs and Benefits
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Effects of artificial migration of susceptible individuals on resistance and fitness of a fenitrothion-resistant strain of Musca domestica (L.) Diptera
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Estimated Resistance of the Malaria Mosquito Anopheles messeae s.l. to the Insecticide Malathion
The malathion resistance of species in the Anopheles maculipennis mosquito group in a habitat near Novosibirsk, Russia was determined and it is suspected that all other Palearctic species of this group would have difficulties harboring the ace-1 mutation that would lead to organophosphate and carbamate resistance. Expand


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The sequence analysis of the Ace gene in several resistant field strains of Drosophila melanogaster resulted in the identification of five point mutations associated with reduced sensitivities to insecticides, suggesting that recombination between resistant alleles preexisting in natural populations is a mechanism by which insects rapidly adapt to new selective pressures. Expand
A Single P450 Allele Associated with Insecticide Resistance in Drosophila
Microarray analysis of all P450s in Drosophila melanogaster shows that DDT-R, a gene conferring resistance to DDT, is associated with overtranscription of a single cytochrome P450 gene, Cyp6g1, which has spread globally. Expand
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DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid
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A point mutation in a Drosophila GABA receptor confers insecticide resistance
The functional expression and novel pharmacology of this GABA receptor are reported and the functionality of a resistance-associated point mutation (alanine to serine) within the second membrane-spanning domain, the region thought to line the chloride ion channel pore is examined. Expand
The genome sequence of Drosophila melanogaster.
The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Expand
Forum: On Resisting Resistance
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