Insecticide Resistance on the Move

  title={Insecticide Resistance on the Move},
  author={Ian Denholm and Gregor J. Devine and Martin S Williamson},
  pages={2222 - 2223}
Understanding the genetics of insecticide resistance is critical to the prediction and management of resistant insects. In their perspective, [Denholm][1] and colleagues describe new work on the genetics of DDT resistance in Drosophila ([Daborn][2] et al .). The data reinforce the hypothesis that resistance can spread quickly to new areas through migration of resistant insects. [1]: [2]:… 

Resistance to Bt Crops; Influence, mechanisms and management strategies

Understanding the Bt resistance mechanisms, including the molecular basis of resistance is important for well-resistance control in Bt crops.

Inheritance Pattern of Temephos Resistance, an Organophosphate Insecticide, in Aedes aegypti (L.)

The present paper reports the mode of inheritance of resistance in laboratory induced temephos resistant and susceptible strains of Ae. aegypti. Homozygous resistant and susceptible strains of Ae.

Identification of Differentially Expressed Genes In Deltamethrin-Resistant Culex pipiens quinquefasciatus

ABSTRACT Culex quinquefasciatus is one of China's major house-dwelling mosquito species and an important vector of filariasis and encephalitis. Chemical treatments represent one of the most

Autosomal inheritance of alphamethrin, a synthetic pyrethroid, resistance in Anopheles stephensi – Liston, a malaria mosquito

The genetics of alphamethrin resistant (amr) gene, a synthetic pyrethroid resistance was studied to determine its mode of inheritance and can be used as genetic marker in A. stephensi, which could be used in several applications in conducting basic and applied genetic research.

Aedes aegypti control: the concomitant role of competition, space and transgenic technologies

Although results presented here focus on the primary vector of dengue fever, they are clearly applicable to the management of any spatially distributed insect pest with over-compensatory population dynamics.

Effects of artificial migration of susceptible individuals on resistance and fitness of a fenitrothion-resistant strain of Musca domestica (L.) Diptera

Findings indicate that fenitrothion resistance in Musca domestica has important fitness costs related with development time, and these costs are mitigated with susceptible migration.

Estimated Resistance of the Malaria Mosquito Anopheles messeae s.l. to the Insecticide Malathion

The malathion resistance of species in the Anopheles maculipennis mosquito group in a habitat near Novosibirsk, Russia was determined and it is suspected that all other Palearctic species of this group would have difficulties harboring the ace-1 mutation that would lead to organophosphate and carbamate resistance.

Evolutionary ecotoxicology of pesticide resistance: a case study in Daphnia

It became clear that the responses to both exposure to single and combined stressors was for several life history variables strongly dependent upon past exposure to carbaryl, indicating that past exposures to pesticides are important and can not be neglected when evaluating responses to current stressors.

Response of the melon aphid, Aphis gossypii, to host‐plant resistance: evidence for high adaptive potential despite low genetic variability

The low genetic polymorphism associated with a strong phenotypic variability highlights the high adaptive potential of A. gossypii and the major role of environmental cues in shaping phenotypesic responses of this aphid to pest management strategies.



Resistance-associated point mutations in insecticide-insensitive acetylcholinesterase.

The sequence analysis of the Ace gene in several resistant field strains of Drosophila melanogaster resulted in the identification of five point mutations associated with reduced sensitivities to insecticides, suggesting that recombination between resistant alleles preexisting in natural populations is a mechanism by which insects rapidly adapt to new selective pressures.

A Single P450 Allele Associated with Insecticide Resistance in Drosophila

Microarray analysis of all P450s in Drosophila melanogaster shows that DDT-R, a gene conferring resistance to DDT, is associated with overtranscription of a single cytochrome P450 gene, Cyp6g1, which has spread globally.

Worldwide migration of amplified insecticide resistance genes in mosquitoes

The results suggest that amplified esterase B2 genes originated from an initial event that has subsequently spread organophosphate insecticide resistance by migration, and that electrophoretically dissimilar esterases B varied considerably.

DDT resistance in Drosophila correlates with Cyp6g1 over-expression and confers cross-resistance to the neonicotinoid imidacloprid

It is shown that pre-existing Rst(2)DDT alleles in turn confer cross-resistance to imidacloprid, and that the hypothesis that resistance to both compounds is associated with over-expression of this P450 gene is tested.

Evidence that the E4 and FE4 esterase genes responsible for insecticide resistance in the aphid Myzus persicae (Sulzer) are part of a gene family.

Evidence is presented that in susceptible aphids the two genes E4 and FE4 are adjacent to each other in a head-to-tail arrangement with E4 upstream of FE4 and with approx.

A point mutation in a Drosophila GABA receptor confers insecticide resistance

The functional expression and novel pharmacology of this GABA receptor are reported and the functionality of a resistance-associated point mutation (alanine to serine) within the second membrane-spanning domain, the region thought to line the chloride ion channel pore is examined.

The genome sequence of Drosophila melanogaster.

The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.

Forum: On Resisting Resistance

The concept of resistance has become one of anthropology's dominant theoretical preoccupations - so influential, in fact, that it threatens to overshadow other aspects of social life, to the