Insect olfactory receptors are heteromeric ligand-gated ion channels

@article{Sato2008InsectOR,
  title={Insect olfactory receptors are heteromeric ligand-gated ion channels},
  author={Koji Sato and Maurizio Pellegrino and Takao Nakagawa and Tatsuro Nakagawa and Leslie B. Vosshall and Kazushige Touhara},
  journal={Nature},
  year={2008},
  volume={452},
  pages={1002-1006}
}
In insects, each olfactory sensory neuron expresses between one and three ligand-binding members of the olfactory receptor (OR) gene family, along with the highly conserved and broadly expressed Or83b co-receptor. The functional insect OR consists of a heteromeric complex of unknown stoichiometry but comprising at least one variable odorant-binding subunit and one constant Or83b family subunit. Insect ORs lack homology to G-protein-coupled chemosensory receptors in vertebrates and possess a… CONTINUE READING
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