Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators.

@article{Ashok1998InsectJH,
  title={Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators.},
  author={Mr. Jammi Ashok and Cheri Turner and Thomas Wilson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 6},
  pages={2761-6}
}
Juvenile hormone analog (JHA) insecticides are relatively nontoxic to vertebrates and offer effective control of certain insect pests. Recent reports of resistance in whiteflies and mosquitoes demonstrate the need to identify and understand genes for resistance to this class of insect growth regulators. Mutants of the Methoprene-tolerant (Met) gene in Drosophila melanogaster show resistance to both JHAs and JH, and previous biochemical studies have demonstrated a mechanism of resistance… CONTINUE READING
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