Insect endosymbiont proliferation is limited by lipid availability

  title={Insect endosymbiont proliferation is limited by lipid availability},
  author={Jeremy K Herren and Juan C Paredes and Fanny Sch{\"u}pfer and Karim Arafah and Philippe Bulet and Bruno Lemaitre},
Spiroplasma poulsonii is a maternally transmitted bacterial endosymbiont that is naturally associated with Drosophila melanogaster. S. poulsonii resides extracellularly in the hemolymph, where it must acquire metabolites to sustain proliferation. In this study, we find that Spiroplasma proliferation specifically depletes host hemolymph diacylglyceride, the major lipid class transported by the lipoprotein, Lpp. RNAi-mediated knockdown of Lpp expression, which reduces the amount of circulating… CONTINUE READING
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Effects of egg-production and of exposure to males on female survival in Drosophila melanogaster

  • L Partridge, A Green, K. Fowler
  • Journal of Insect Physiology 33:745–749. doi: 10…
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