Insect P450 inhibitors and insecticides: challenges and opportunities.

  title={Insect P450 inhibitors and insecticides: challenges and opportunities.},
  author={Ren{\'e} Feyereisen},
  journal={Pest management science},
  volume={71 6},
P450 enzymes are encoded by a large number of genes in insects, often over a hundred. They play important roles in insecticide metabolism and resistance, and growing numbers of P450 enzymes are now known to catalyse important physiological reactions, such as hormone metabolism or cuticular hydrocarbon synthesis. Ways to inhibit P450 enzymes specifically or less specifically are well understood, as P450 inhibitors are found as drugs, as fungicides, as plant growth regulators and as insecticide… CONTINUE READING
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