Input-selective potentiation and rebalancing of primary sensory cortex afferents by endogenous acetylcholine

@article{Kuo2009InputselectivePA,
  title={Input-selective potentiation and rebalancing of primary sensory cortex afferents by endogenous acetylcholine},
  author={Min-Ching Kuo and Douglas Rasmusson and Hans C Dringenberg},
  journal={Neuroscience},
  year={2009},
  volume={163},
  pages={430-441}
}

Figures from this paper

Cholinergic-mediated response enhancement in barrel cortex layer V pyramidal neurons.
TLDR
ACh modified the excitatory/inhibitory balance and switched L5 pyramidal neurons to a bursting mode that caused a potent and sustained response enhancement with possible fundamental consequences for the function of the barrel cortex.
Modulation of high- and low-frequency components of the cortical local field potential via nicotinic and muscarinic acetylcholine receptors in anesthetized mice.
TLDR
It is concluded that the activation of nicotinic and muscarinic ACh receptors in neocortex exerts several effects that are reflected in distinct frequency bands of the cortical LFP in urethane-anesthetized mice.
Electronically induced contrast enhancement in whisker S1 cortical response fields
  • L. M. Kraus, J. Francis
  • Biology, Psychology
    2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • 2014
TLDR
It is shown that pairing whisker deflection with electrical stimulation of the magnocellular basal nucleus (BN) causes an increase in the center-surround contrast of the treated whisker's cortical response field (CRF), while unpaired BN stimulation causes a more general increases in S1 responsiveness, without contrast modulation.
Basal forebrain activation controls contrast sensitivity in primary visual cortex
TLDR
It is concluded that BF activation has a strong influence on contrast sensitivity in V1 and suggested that, in addition to cholinergic modulation, the BF GABAergic projections play a crucial role in the impact of BF DBS on cortical activity.
Fast Modulation of Visual Perception by Basal Forebrain Cholinergic Neurons
TLDR
It is shown that basal forebrain cholinergic neurons rapidly regulate cortical activity and visual perception in awake, behaving mice, and optogenetic activation of the cholinergy neurons or their V1 axon terminals improved performance of a visual discrimination task on a trial-by-trial basis.
Muscarinic and Nicotinic Modulation of Thalamo-Prefrontal Cortex Synaptic Pasticity In Vivo
TLDR
The results show that HFS did not affect mPFC responses in vehicle-injected rats, but induced a delayed-onset LTP with distinct effects when applied following PILO or NIC, and LFS induced a stable LTD in control subjects, but was unable to induce LTD when applied after PILo or NIC.
Modulation of Specific Sensory Cortical Areas by Segregated Basal Forebrain Cholinergic Neurons Demonstrated by Neuronal Tracing and Optogenetic Stimulation in Mice
TLDR
It is revealed that the BF is a heterogeneous area in which neurons projecting to different cortical areas are segregated into different neuronal groups, suggesting that cholinergic projections to the cortex are organized into segregated pools of neurons that may modulate specific cortical areas.
Muscarinic and Nicotinic Contribution to Contrast Sensitivity of Macaque Area V1 Neurons
TLDR
In the majority of cells receptor blockade was best described by a response gain model (a multiplicative scaling of responses), indicating that ACh is involved in signal enhancement, not saliency filtering in macaque V1.
...
1
2
3
...

References

SHOWING 1-10 OF 74 REFERENCES
Heterosynaptic facilitation of in vivo thalamocortical long-term potentiation in the adult rat visual cortex by acetylcholine.
TLDR
It is concluded that heterosynaptic facilitation of V1 plasticity by ACh extends beyond early postnatal maturation periods and acts to convert weak potentiation into pronounced, long-lasting increases in synaptic strength.
Long-term cholinergic enhancement of evoked potentials in rat hindlimb somatosensory cortex displays characteristics of long-term potentiation
TLDR
Long-term cholinergic enhancement, attributable to disinhibition and increased release of acetylcholine in the cortex during neuronal excitation by other sources, and so named because it is blocked by atropine, may be a form of long-term potentiation.
A functional role of cholinergic innervation to neurons in the cat visual cortex.
TLDR
The results suggest that the cholinergic innervation to cortical neurons may play a role in improvement of the S/N ratio of information processing in the striate cortex and in facilitation of sending processed informations to other visual centers.
Laminar distribution of cholinergic- and serotonergic-dependent plasticity within kitten visual cortex.
Cholinergic suppression specific to intrinsic not afferent fiber synapses in rat piriform (olfactory) cortex.
TLDR
Differences in the cholinergic suppression of afferent and intrinsic fiber synaptic transmission were studied in the rat piriform cortex and the increase in the level of facilitation accompanying suppression suggests a presynaptic mechanism.
Cholinergic modulation of response properties and orientation tuning of neurons in primary visual cortex of anaesthetized Marmoset monkeys
TLDR
It is found that acetylcholine caused a broadening of the orientation tuning in the majority of cells, while tuning functions became sharper in only a minority of cells; this findings are discussed in the context of dynamic control of feed‐forward and lateral/feedback connectivity by acetylCholine.
...
1
2
3
4
5
...