Inotropic Effects of Prostaglandin D2 and E1 on the Newborn Rabbit Heart

Abstract

ABSTRACT: This study determines the inotropic effects of prostaglandin D2 (PGD2) and prostaglandin E1 (PGE1) in the isolated, arterial perfused newborn (NB) and adult (A) rabbit heart.Significant positive inotropism of PGD2 was observed at all concentrations studied (1 × 10-17 to 1 × 10-7 M) in the two age groups; the effect in the NB was significantly… (More)
DOI: 10.1203/00006450-198412000-00010

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