Inotrope and vasopressor therapy of septic shock.

@article{Hollenberg2011InotropeAV,
  title={Inotrope and vasopressor therapy of septic shock.},
  author={Steven M. Hollenberg},
  journal={Critical care nursing clinics of North America},
  year={2011},
  volume={23 1},
  pages={
          127-48
        }
}
The ultimate goals of hemodynamic therapy in shock are to restore effective tissue perfusion and to normalize cellular metabolism. In sepsis, both global and regional perfusion must be considered. In addition, mediators of sepsis can perturb cellular metabolism, leading to inadequate use of oxygen and other nutrients despite adequate perfusion; one would not expect organ dysfunction mediated by such abnormalities to be corrected by hemodynamic therapy. Despite the complex pathophysiology of… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 128 REFERENCES

Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best

D De Backer, J Creteur, E Silva
  • Crit Care Med
  • 2003
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Regional blood flow and oxygen transport in septic shock.

  • Critical care medicine
  • 1993
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL