Inositol trisphosphate-induced Ca2+ signaling modulates auxin transport and PIN polarity.

@article{Zhang2011InositolTC,
  title={Inositol trisphosphate-induced Ca2+ signaling modulates auxin transport and PIN polarity.},
  author={Jing Zhang and Steffen Vanneste and Philip B Brewer and Marta Michniewicz and Peter Grones and J{\"u}rgen Kleine-Vehn and Christian L{\"o}fke and Thomas Teichmann and Agnieszka Bielach and Bernard Cannoot and Kl{\'a}ra Hoyerov{\'a} and Xu Chen and Hong-Wei Xue and Eva Benkov{\'a} and Eva Za{\vz}{\'i}malov{\'a} and Jiř{\'i} Friml},
  journal={Developmental cell},
  year={2011},
  volume={20 6},
  pages={855-66}
}
The phytohormone auxin is an important determinant of plant development. Directional auxin flow within tissues depends on polar localization of PIN auxin transporters. To explore regulation of PIN-mediated auxin transport, we screened for suppressors of PIN1 overexpression (supo) and identified an inositol polyphosphate 1-phosphatase mutant (supo1), with elevated inositol trisphosphate (InsP(3)) and cytosolic Ca(2+) levels. Pharmacological and genetic increases in InsP(3) or Ca(2+) levels also… CONTINUE READING

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