Inositol polyphosphate multikinase signaling in the regulation of metabolism

@inproceedings{Lee2012InositolPM,
  title={Inositol polyphosphate multikinase signaling in the regulation of metabolism},
  author={Joo-Young Lee and Young-Ran Kim and Jina Park and Sung Hyun Kim},
  booktitle={Annals of the New York Academy of Sciences},
  year={2012}
}
Inositol phosphates (IPs) act as signaling messengers to regulate various cellular processes such as growth. Inositol polyphosphate multikinase (IPMK) generates inositol tetrakis- and pentakisphosphates (IP₄ and IP₅), acting as a key enzyme for inositol polyphosphate biosynthesis. IPMK was initially discovered as an essential subunit of the arginine-sensing transcription complex in budding yeast. In mammals, IPMK is also known as a physiologically important phosphatidylinositol 3 kinase (PI3K… CONTINUE READING
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