Inositol biosynthesis: Candida albicans and Saccharomyces cerevisiae genes share common regulation.

@article{Klig1991InositolBC,
  title={Inositol biosynthesis: Candida albicans and Saccharomyces cerevisiae genes share common regulation.},
  author={L. S. Klig and Bruno Antonsson and Erika Schmid and Lisa Friedli},
  journal={Yeast},
  year={1991},
  volume={7 4},
  pages={325-36}
}
The Candida albicans inositol biosynthetic gene and its regulation have been studied. The gene, CalNO1, was cloned on a multicopy vector by complementation of a Saccharomyces cerevisae mutant strain. Southern blot analysis established that the cloned DNA was C. albicans genomic DNA in origin; neither rearrangements nor pseudogenes were evident. Blot hybridization analysis using RNA isolated from C. albicans revealed that a single RNA species (1.8 kilobases) was homologous to the cloned DNA… CONTINUE READING