Inositol 1,4,5-trisphosphate accumulation in brain of lithium-treated rats

@article{Ishima1993Inositol1A,
  title={Inositol 1,4,5-trisphosphate accumulation in brain of lithium-treated rats},
  author={Yoshio Ishima and Michiyo Fujimagari and Yasuo Masuzawa and Keizo Waku},
  journal={Lipids},
  year={1993},
  volume={28},
  pages={577-581}
}
The mechanism of action of lithium as a drug for patients with affective disorders was investigated. Three-week-old male rats were orally administered 2.7 mEq Li2CO3/kg/d for 1 or 3 wk, and phosphatidylinositol (PI), phosphatidylinositol 4-phosphate (PIP), phosphatidylinositol 4,5-bisphosphate (PIP2), inositol phosphate (IP), inositol diphosphate (IP2) and… CONTINUE READING