Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines.

  title={Inositol-1,4,5-trisphosphate-3-kinase-A controls morphology of hippocampal dendritic spines.},
  author={J K{\"o}ster and Birthe Leggewie and Christine Blechner and Nicola Brandt and Lars Fester and Gabriele M Rune and Michaela Schweizer and Stefan Kindler and Sabine Windhorst},
  journal={Cellular signalling},
  volume={28 1},
Long-lasting synaptic plasticity is often accompanied by morphological changes as well as formation and/or loss of dendritic spines. Since the spine cytoskeleton mainly consists of actin filaments, morphological changes are primarily controlled by actin binding proteins (ABPs). Inositol-1,4,5-trisphosphate-3-kinase-A (ITPKA) is a neuron-specific, actin… CONTINUE READING