Inorganic pyrophosphatase (PPA1) is a negative prognostic marker for human gastric cancer.

@article{Yang2015InorganicP,
  title={Inorganic pyrophosphatase (PPA1) is a negative prognostic marker for human gastric cancer.},
  author={Yingchi Yang and Jun Cai and Jie Yin and Dong Wang and Zhigang Bai and Jun Zhang and Kangli Wang and Guanzhen Yu and Zhongtao Zhang},
  journal={International journal of clinical and experimental pathology},
  year={2015},
  volume={8 10},
  pages={12482-90}
}
Inorganic pyrophosphatase (PPA1) is an enzyme which has been found to be upregulated in various tumors, yet its profile in gastrointestinal cancers has not systemically investigated. In present study, gastrointestinal tissue microarrays were used to evaluate PPA1 expression and the association of PPA1 expression with clinical outcomes was determined for patients with gastric cancer by immunohistochemistry. Overexpression of PPA1 was observed in cancers of the esophagus, stomach, and… CONTINUE READING

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