Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice.

  title={Inorganic phosphate homeostasis in sodium-dependent phosphate cotransporter Npt2b⁺/⁻ mice.},
  author={Akiko Ohi and Etsuyo Hanabusa and Otoya Ueda and Hiroko Segawa and Naoshi Horiba and Ichiro Kaneko and Shoji Kuwahara and Tomo Mukai and Shohei Sasaki and Rieko Tominaga and Junya Furutani and Fumito Aranami and Shuichi Ohtomo and Yumiko Oikawa and Yousuke Kawase and Naoko A. Wada and Takanori Tachibe and Mami Kakefuda and Hiromi Tateishi and Kaoru Matsumoto and Sawako Tatsumi and Shinsuke Kido and Naoshi Fukushima and Kou-ichi Jishage and Ken-Ichi Miyamoto},
  journal={American journal of physiology. Renal physiology},
  volume={301 5},
An inorganic phosphate (P(i))-restricted diet is important for patients with chronic kidney disease and patients on hemodialysis. Phosphate binders are essential for preventing hyperphosphatemia and ectopic calcification. The sodium-dependent P(i) (Na/P(i)) transport system is involved in intestinal P(i) absorption and is regulated by several factors. The type II sodium-dependent P(i) transporter Npt2b is expressed in the brush-border membrane in intestinal epithelial cells and transports P(i… CONTINUE READING


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Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate.

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