Innovative pulmonary preservation of non-heart-beating donor grafts in experimental lung transplantation.

@article{Wittwer2004InnovativePP,
  title={Innovative pulmonary preservation of non-heart-beating donor grafts in experimental lung transplantation.},
  author={Thorsten Wittwer and Ulrich Friedrich Wilhelm Franke and Antonia Fehrenbach and Matthias Ochs and Tim Sandhaus and Niels Dreyer and Joachim Richter and Thorsten Wahlers},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2004},
  volume={26 1},
  pages={144-50}
}
OBJECTIVE Lung transplantation is limited by scarcity of donor organs. Lung retrieval from non-heart-beating donors (NHBD) might have the potential to extend the donor pool and has been reported recently. However, no studies in NHBD exist using the novel approach of retrograde preservation with Perfadex solution. METHODS Asystolic heparinized pigs (n = 5/group) were continuously ventilated for 90, 180 or 300 min of warm ischemia. Lungs were then retrogradely preserved with Perfadex and stored… CONTINUE READING