Innovative lead discovery strategies for tropical diseases

  title={Innovative lead discovery strategies for tropical diseases},
  author={Solomon Nwaka and Alan Hudson},
  journal={Nature Reviews Drug Discovery},
Lead discovery is currently a key bottleneck in the pipeline for much-needed novel drugs for tropical diseases such as malaria, tuberculosis, African sleeping sickness, leishmaniasis and Chagas disease. Here, we discuss the different approaches to lead discovery for tropical diseases and emphasize a coordination strategy that involves highly integrated partnerships and networks between scientists in academic institutions and industry in both wealthy industrialized countries and disease-endemic… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
175 Citations
65 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 175 extracted citations


Publications referenced by this paper.
Showing 1-10 of 65 references

Collaborating to find new approaches to tropical diseases

  • D. Perrin, A. Scheer, T. Wells
  • Eur . Pharma . Rev .
  • 2006

Global mapping of pharmacological space

  • V. PaoliniG.
  • Nature Biotechnol .
  • 2006

Similar Papers

Loading similar papers…