Innovative lead discovery strategies for tropical diseases

@article{Nwaka2006InnovativeLD,
  title={Innovative lead discovery strategies for tropical diseases},
  author={Solomon Nwaka and Alan Hudson},
  journal={Nature Reviews Drug Discovery},
  year={2006},
  volume={5},
  pages={941-955}
}
Lead discovery is currently a key bottleneck in the pipeline for much-needed novel drugs for tropical diseases such as malaria, tuberculosis, African sleeping sickness, leishmaniasis and Chagas disease. Here, we discuss the different approaches to lead discovery for tropical diseases and emphasize a coordination strategy that involves highly integrated partnerships and networks between scientists in academic institutions and industry in both wealthy industrialized countries and disease-endemic… CONTINUE READING
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