Innovative approaches to treat steroid-resistant or steroid refractory GVHD

Abstract

First-line treatment of GVHD is based on steroids and produces sustained responses in 50–80% of patients with acute GVHD (aGVHD) and 40–50% of patients with chronic GVHD (cGVHD) depending on the initial disease severity. Non-responding children are offered second-line therapy with combinations of various agents, but currently available agents have not… (More)
DOI: 10.1038/bmt.2008.294

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