Innovative approaches to anti-arrhythmic drug therapy

@article{Nattel2006InnovativeAT,
  title={Innovative approaches to anti-arrhythmic drug therapy},
  author={Stanley Nattel and Leif Carlsson},
  journal={Nature Reviews Drug Discovery},
  year={2006},
  volume={5},
  pages={1034-1049}
}
Normal cardiac function requires an appropriate and regular beating rate (cardiac rhythm). When the heart rhythm is too fast or too slow, cardiac function can be impaired, with derangements that vary from mild symptoms to life-threatening complications. Irregularities, particularly those involving excessively fast or slow rates, constitute cardiac 'arrhythmias'. In the past, drug treatment of cardiac arrhythmias has proven difficult, both because of inadequate effectiveness and a risk of… CONTINUE READING
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Electrophysiological and atrial antiarrhythmic effects of a novel IKur/Kv1.5 blocker in dogs with atrial tachycardia remodeling

  • A Shiroshita-Takeshita
  • Heart Rhythm 3,
  • 2006

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