Innovative Approaches for the Treatment of Depression: Targeting the HPA Axis

@article{Thomson2007InnovativeAF,
  title={Innovative Approaches for the Treatment of Depression: Targeting the HPA Axis},
  author={Fiona Thomson and Mark Craighead},
  journal={Neurochemical Research},
  year={2007},
  volume={33},
  pages={691-707}
}
Altered activity of the hypothalamic pituitary adrenal (HPA) axis is one of the most commonly observed neuroendocrine abnormalities in patients suffering from major depressive disorder (MDD). Altered cortisol secretion can be found in as many as 80% of depressed patients. This observation has led to intensive clinical and preclinical research aiming to… CONTINUE READING