Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution.

@article{Werner2010InnovativeNB,
  title={Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers--a Swiss contribution.},
  author={S{\"o}ren Werner and Regine Eibl and Christine Lettenbauer and Marcel R{\"o}ll and Dieter Eibl and Maria L. A. de Jesus and Xiaowei Zhang and M. Stettler and St{\'e}phanie Tissot and C{\'e}dric B{\"u}rki and Gilles Broccard and Markus K{\"u}hner and Rolf Tanner and L. Baldi and David Hacker and F. M. Wurm},
  journal={Chimia},
  year={2010},
  volume={64 11},
  pages={819-23}
}
Innovative mixing principles in bioreactors, for example using the rocking of a platform to induce a backwards and forwards 'wave', or using orbital shaking to generate a 'wave' that runs round in a cylindrical container, have proved to be successful for the suspension cultures of cells, especially when combined with disposable materials. This article… CONTINUE READING