Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

@article{Moro2010InnatePO,
  title={Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells},
  author={Kazuyo Moro and Taketo Yamada and Masanobu Tanabe and Tsutomu Takeuchi and Tomokatsu Ikawa and Hiroshi Kawamoto and Jun-ichi Furusawa and Masashi Ohtani and Hideki Fujii and Shigeo Koyasu},
  journal={Nature},
  year={2010},
  volume={463},
  pages={540-544}
}
Innate immune responses are important in combating various microbes during the early phases of infection. Natural killer (NK) cells are innate lymphocytes that, unlike T and B lymphocytes, do not express antigen receptors but rapidly exhibit cytotoxic activities against virus-infected cells and produce various cytokines. Here we report a new type of innate lymphocyte present in a novel lymphoid structure associated with adipose tissues in the peritoneal cavity. These cells do not express… CONTINUE READING
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