Innate lymphoid cells and allergic inflammation.

@article{Kim2013InnateLC,
  title={Innate lymphoid cells and allergic inflammation.},
  author={Brian S Kim and Elia D. Tait Wojno and David Artis},
  journal={Current opinion in immunology},
  year={2013},
  volume={25 6},
  pages={738-44}
}
Group 2 innate lymphoid cells (ILC2s) play critical roles in anti-helminth immunity and airway epithelial repair. Recently, these cells have also emerged as key players in the development of allergic inflammation at multiple barrier surfaces. ILC2s arise from common lymphoid progenitors in the bone marrow, are dependent on the transcription factors RORα, GATA3, and TCF-1 and produce the type 2 cytokines IL-4, IL-5, IL-9, and/or IL-13. The epithelial cell-derived cytokines IL-25, IL-33, and TSLP… CONTINUE READING

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