Innate lymphoid cells: A new paradigm in immunology

  title={Innate lymphoid cells: A new paradigm in immunology},
  author={G{\'e}rard Eberl and Marco Colonna and James P Di Santo and Andrew N. J. McKenzie},
Innate lymphoid cells (ILCs) are a growing family of immune cells that mirror the phenotypes and functions of T cells. However, in contrast to T cells, ILCs do not express acquired antigen receptors or undergo clonal selection and expansion when stimulated. Instead, ILCs react promptly to signals from infected or injured tissues and produce an array of secreted proteins termed cytokines that direct the developing immune response into one that is adapted to the original insult. The complex cross… CONTINUE READING

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