Innate immunity in lophotrochozoans: the annelids.

@article{Salzet2006InnateII,
  title={Innate immunity in lophotrochozoans: the annelids.},
  author={Michel Salzet and Aur{\'e}lie Tasiemski and Edwin Cooper},
  journal={Current pharmaceutical design},
  year={2006},
  volume={12 24},
  pages={
          3043-50
        }
}
Innate immunity plays a major role as a first defense against microbes. Effectors of the innate response include pattern recognition receptors (PRR), phagocytic cells, proteolytic cascades and peptides/proteins with antimicrobial properties. Each element of these events has been well studied in vertebrates and in some invertebrates such as annelids. From these different researches, it appears that mammalian innate immunity could be considered as a mosaic of invertebrate immune responses… 
Antimicrobial peptides in annelids
TLDR
An overview of the variety of AMPs identified in the three classes of annelids, i.e. polychaetes, oligochaetes and achaete is given, suggesting that immune defense of annalids seems to be principally developed as cellular immunity.
Invertebrate Innate Immune Defenses
TLDR
This chapter reviews the currently available data from the simplest metazoan species, the Porifera and Cnidaria, in an attempt to trace the origin of essential elements of the innate immune system.
The ancestry and cumulative evolution of immune reactions.
  • J. Dzik
  • Biology
    Acta biochimica Polonica
  • 2010
TLDR
The adaptive immune system of mammals is also deeply rooted in the metazoan evolution, and its functional convergence was presumably enabled by the general similarity of the lectin-like recognition domain three-dimensional structure.
Immunity of the lugworm Arenicola marina: cells and molecules
TLDR
This work discusses immune responses of the polychete Arenicola marina, the lugworm, and presents the synopsis on antimicrobial peptides arenicins: their structure, function and therapeutic potential.
Immuno-defense Strategy in Earthworms: A Review Article
TLDR
Income immunity presents in all organisms as their natural immunity since birth upto the whole life of organisms and is considered as most primitive and simplest form of immunity.
Platyhelminthes: Molecular Dissection of the Planarian Innate Immune System
TLDR
This work focuses on the planarian model system as a tractable paradigm to identify evolutionarily conserved mechanisms of innate immunity that can be further exploited in clinical settings to induce rapid clearance of pathogenic bacteria and modulation of regenerative events.
Immunology of Invertebrates: Cellular
Circulating blood cells are the primary mediators of immunity in invertebrates, carrying out the phagocytic, pathogen trapping and other inflammatory responses that protect invertebrates against
Defense and Immune Systems
The complex of defensive strategies characterizing invertebrate immune systems and response is reviewed. These include the role of pathogen recognition molecules and evolutionary aspects concerning a
...
...

References

SHOWING 1-10 OF 70 REFERENCES
Immune defense and biological responses induced by toxics in Annelida
TLDR
The phylum Annelida comprises primitive coelomates that possess specially developed cellular immunity against pathogens, but no specificity analogous to vertebrate antibodies has been revealed, except for weak specificity of some antigen-binding proteins.
Digging for innate immunity since Darwin and Metchnikoff.
TLDR
The cellular and humoral components of the earthworm system function to distinguish between self and not self, dispose of internal (cancer?), damaged components and external antigens (microbes), and the evolutionary context is discussed at the end of this article.
Antimicrobial peptides: mediators of innate immunity as templates for the development of novel anti-infective and immune therapeutics.
TLDR
The "classical" functions of 3 classes of antimicrobial molecules, namely defensins, cathelicidins, and the four-disulfide core proteins secretory leukocyte proteinase inhibitor (SLPI) and elafin are reviewed and novel properties of these molecules that have been highlighted by recent studies are described.
Vertebrate innate immunity resembles a mosaic of invertebrate immune responses.
Antibacterial properties of hemerythrin of the sand worm Nereis diversicolor.
TLDR
These results reflect that MPII in conjunction with others partners like lysozyme act as defence molecule for the sand worm.
Leeches: immune response, angiogenesis and biomedical applications.
TLDR
The responses of leeches to different kinds of stimuli (infections following non-self agent attacks, surgical lesions, grafts), which are responsible for positive and negative modulation of angiogenesis, are described.
Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity.
TLDR
The data demonstrate that the innate immune response in the leech involves a cysteine proteinase inhibitor that is not found in ecdysozoan models, such as Drosophila melanogaster or Caenorhabditis elegans, and so underlines the great need for information about innate immunity mechanisms in different invertebrate groups.
Innate immunity and the heart.
TLDR
In this review, a general overview of the components of innate immunity with a focus on humoral factors, their role in the response to foreign pathogens, and their potential role inThe response to tissue injury is provided.
Adaptability of the coccidian Coelotropha to parasitism.
Annelid humoral immunity: cell lysis in earthworms.
TLDR
The earthworm’s importance in understanding the capacity of coelomic fluid to effect lysis by means of a protein which has been referred to as Eiseniapore is significant as indicated by the recent increase in molecular studies relevant to lysis.
...
...