Innate immunity in human newborn infants: prematurity means more than immaturity.

  title={Innate immunity in human newborn infants: prematurity means more than immaturity.},
  author={Tobias Strunk and Andrew Currie and Peter Richmond and Karen N. Simmer and David Burgner},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  volume={24 1},
Neonates, particularly those born prematurely, are exquisitely vulnerable to life-threatening infections. This increased susceptibility to infection is maintained into childhood. Despite the considerable human and economic cost of infection-related neonatal morbidity and mortality, the mechanisms underlying this heightened susceptibility are only partly understood. It is increasingly recognised that innate immune responses are key to the protection against infection early in life, and emerging… CONTINUE READING
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