Innate immunity and organ transplantation: focus on lung transplantation.

@article{Kreisel2013InnateIA,
  title={Innate immunity and organ transplantation: focus on lung transplantation.},
  author={Daniel Kreisel and Daniel R Goldstein},
  journal={Transplant international : official journal of the European Society for Organ Transplantation},
  year={2013},
  volume={26 1},
  pages={2-10}
}
Ischemia reperfusion injury (IRI) that occurs with solid organ transplantation activates the innate immune system to induce inflammation. This leads to enhanced acute allograft rejection, impaired transplant tolerance and accelerated progression of chronic rejection. In this review, we discuss the innate immune signaling pathways that have been shown to play a role in organ transplantation. In particular, we focus on Toll-like receptor signaling pathways and how they have influenced outcomes… CONTINUE READING

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Creatine supplementation attenuates pulmonary and systemic effects of lung ischemia and reperfusion injury.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation • 2016
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Adaptive and innate immune responses in a rat orthotopic lung transplant model of chronic lung allograft dysfunction.

Transplant international : official journal of the European Society for Organ Transplantation • 2015

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