Innate immunity and cardiomyocytes in ischemic heart disease.

  title={Innate immunity and cardiomyocytes in ischemic heart disease.},
  author={Li Lin and Anne A Knowlton},
  journal={Life sciences},
  volume={100 1},
Myocardial ischemia/reperfusion (I/R) is the most common cause of myocardial inflammation, which is primarily a manifestation of the innate immune responses. Innate immunity is activated when pattern recognition receptors (PRRs) respond to molecular patterns common to microbes and to danger signals expressed by injured or infected cells, so called pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). The expression of various PRRs in cardiomyocytes and… CONTINUE READING
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