Innate immune system and tissue regeneration in planarians: an area ripe for exploration.

@article{Peiris2014InnateIS,
  title={Innate immune system and tissue regeneration in planarians: an area ripe for exploration.},
  author={Tanuja Harshani Peiris and Katrina K. Hoyer and N{\'e}stor J Oviedo},
  journal={Seminars in immunology},
  year={2014},
  volume={26 4},
  pages={295-302}
}
The immune system has been implicated as an important modulator of tissue regeneration. However, the mechanisms driving injury-induced immune response and tissue repair remain poorly understood. For over 200 years, planarians have been a classical model for studies on tissue regeneration, but the planarian immune system and its potential role in repair is largely unknown. We found through comparative genomic analysis and data mining that planarians contain many potential homologs of the innate… CONTINUE READING
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