Innate immune responses to infection.

  title={Innate immune responses to infection.},
  author={Michael F Tosi},
  journal={The Journal of allergy and clinical immunology},
  volume={116 2},
  pages={241-9; quiz 250}
  • Michael F Tosi
  • Published 2005 in The Journal of allergy and clinical immunology
The human host survives many infectious challenges in the absence of preexisting specific (adaptive) immunity because of the existence of a separate set of protective mechanisms that do not depend on specific antigenic recognition. These antigen-independent mechanisms constitute innate immunity. Antimicrobial peptides are released at epithelial surfaces and disrupt the membranes of many microbial pathogens. Toll-like receptors on epithelial cells and leukocytes recognize a range of microbial… CONTINUE READING

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