Innate immune responses against Cryptosporidium parvum infection.

  title={Innate immune responses against Cryptosporidium parvum infection.},
  author={Vincent McDonald and Daniel S. Korbel and Farah M. Barakat and Naheed Choudhry and Franz Petry},
  journal={Parasite immunology},
  volume={35 2},
Cryptosporidium parvum infects intestinal epithelial cells and is commonly the parasite species involved in mammalian cryptosporidiosis, a major health problem for humans and neonatal livestock. In mice, immunologically mediated elimination of C. parvum requires CD4+ T cells and IFN-γ. However, innate immune responses also have a significant protective role in both adult and neonatal mice. NK cells and IFN-γ have been shown to be important components in immunity in T and B cell-deficient mice… CONTINUE READING


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