Innate immune mucin production via epithelial cell surface signaling: relationship to allergic disease.

@article{Nadel2007InnateIM,
  title={Innate immune mucin production via epithelial cell surface signaling: relationship to allergic disease.},
  author={Jay A. Nadel},
  journal={Current opinion in allergy and clinical immunology},
  year={2007},
  volume={7 1},
  pages={57-62}
}
  • Jay A. Nadel
  • Published 2007 in
    Current opinion in allergy and clinical…
PURPOSE OF REVIEW Airway epithelial surface signaling is provided by epidermal growth factor receptor (EGFR) phosphorylation, resulting in innate immune responses. Here the focus is the EGFR cascades leading to immune mucin responses. The review is timely because recent discoveries implicate these pathways in multiple innate immune defenses in addition to mucin production. RECENT FINDINGS EGFR activation causes mucin production and inhibition prevents mucin production by multiple stimuli. The… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…