Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection.

@article{Dring2011InnateIG,
  title={Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection.},
  author={M M Dring and Maria H Morrison and Brian Patrick McSharry and Kieran J. Guinan and Richard Hagan and Cliona O'Farrelly and Clair M Gardiner},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 14},
  pages={
          5736-41
        }
}
Hepatitis C is a common infection with significant morbidity and mortality, and only a minority of patients successfully clear the infection. Identification of factors that influence disease progression in HCV infection is difficult owing to the lack of well-defined patient cohorts. However, recent evidence supports a role for the innate immune system in virus clearance. In this study, we investigated innate immune genes for their contribution to disease progression in a unique cohort of well… CONTINUE READING

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