Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition.

@article{Cvetanovic2004InnateID,
  title={Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition.},
  author={Marija Cvetanovic and David S. Ucker},
  journal={Journal of immunology},
  year={2004},
  volume={172 2},
  pages={880-9}
}
Physiological cell death is a process the purpose of which is the elimination of functionally inappropriate cells in a manner that does not elicit an inflammatory response. We have shown previously that the ability of apoptotic corpses to be recognized by macrophages and to modulate the proinflammatory responses of those cells represents paradoxically a… CONTINUE READING