Innate immune cell recruitment in the fetus and neonate.

  title={Innate immune cell recruitment in the fetus and neonate.},
  author={Claudia F. Nussbaum and Markus Sperandio},
  journal={Journal of reproductive immunology},
  volume={90 1},
Recruitment of innate immune cells from the vasculature into infected tissue is a key event in primary host defense against invading pathogens. This highly regulated process requires a functional interplay of specialized adhesion molecules and involves a series of steps leading from rolling of leukocytes along the endothelium to firm adhesion and finally transmigration. In the developing fetus, innate immune functions are ontogenetically regulated and show increasing maturation throughout… CONTINUE READING