Innate immune activation of swine intestinal epithelial cell lines (IPEC-J2 and IPI-2I) in response to LPS from Salmonella typhimurium.

@article{Arce2010InnateIA,
  title={Innate immune activation of swine intestinal epithelial cell lines (IPEC-J2 and IPI-2I) in response to LPS from Salmonella typhimurium.},
  author={Cristina Arce and Mar{\'i}a Ram{\'i}rez-Boo and Concepci{\'o}n Lucena and Juan Jos{\'e} Garrido},
  journal={Comparative immunology, microbiology and infectious diseases},
  year={2010},
  volume={33 2},
  pages={161-74}
}
The innate immune system has the basic function of identifying and eradicating microbial invaders and alerting the adaptative immune system to their presence. In this study, the porcine intestinal innate immune response was evaluated by analysing the expression of TLRs, cytokines and chemokines in two porcine epithelial cell lines from different regions: IPEC-J2 (jejunum) and IPI-2I (ileum). Both cells lines were stimulated with 1microg of LPS from Salmonella typhimurium. RNA was collected at… CONTINUE READING

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