Innate and adaptive immunity in atherosclerosis

  title={Innate and adaptive immunity in atherosclerosis},
  author={Ren{\'e} R. Sevag Packard and Andrew H. Lichtman and P. Scott Libby},
  journal={Seminars in Immunopathology},
Atherosclerosis, a chronic inflammatory disorder, involves both the innate and adaptive arms of the immune response that mediate the initiation, progression, and ultimate thrombotic complications of atherosclerosis. Most fatal thromboses, which may manifest as acute myocardial infarction or ischemic stroke, result from frank rupture or superficial erosion of the fibrous cap overlying the atheroma, processes that occur in inflammatorily active, rupture-prone plaques. Appreciation of the… CONTINUE READING
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