Innate and adaptive determinants of host susceptibility to medically important fungi.

@article{Huffnagle2003InnateAA,
  title={Innate and adaptive determinants of host susceptibility to medically important fungi.},
  author={Gary B Huffnagle and George S Deepe},
  journal={Current opinion in microbiology},
  year={2003},
  volume={6 4},
  pages={
          344-50
        }
}
The host response is the outcome of an interplay between innate immunity, adaptive immunity (Th1, Th2, T regulatory cells, B cells and antibodies) and fungal virulence factors. Dendritic cells are the gatekeepers between innate and adaptive immunity and have been the intense focus of recent studies on innate immunity to fungi because of their ability to distinguish between different forms of a fungal species, to drive Th1 versus Th2 versus T regulatory responses, and potentially be modulated by… CONTINUE READING
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