Innate and Adaptive Immunity in Calcific Aortic Valve Disease

@inproceedings{Mathieu2015InnateAA,
  title={Innate and Adaptive Immunity in Calcific Aortic Valve Disease},
  author={Patrick Mathieu and Rihab Bouchareb and Marie-Chlo{\'e} Boulanger},
  booktitle={Journal of immunology research},
  year={2015}
}
Calcific aortic valve disease (CAVD) is the most common heart valve disorder. CAVD is a chronic process characterized by a pathologic mineralization of valve leaflets. Ectopic mineralization of the aortic valve involves complex relationships with immunity. Studies have highlighted that both innate and adaptive immunity play a role in the development of CAVD. In this regard, accumulating evidence indicates that fibrocalcific remodelling of the aortic valve is associated with activation of the NF… CONTINUE READING
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