Innate Immunity, Environmental Drivers, and Disease Ecology of Marine and Freshwater Invertebrates

@article{Mydlarz2006InnateIE,
  title={Innate Immunity, Environmental Drivers, and Disease Ecology of Marine and Freshwater Invertebrates},
  author={Laura Mydlarz and Laura E. Jones and C. Drew Harvell},
  journal={Annual Review of Ecology, Evolution, and Systematics},
  year={2006},
  volume={37},
  pages={251-288}
}
Despite progress in the past decade, researchers struggle to evaluate the hypothesis that environmental conditions compromise immunity and facilitate new disease outbreaks. In this chapter, we review known immunological mechanisms for selected phyla and find that there are critical response pathways common to all invertebrates. These include the prophenoloxidase pathway, wandering phagocytic cells, cytotoxic effector responses, and antimicrobial compounds. To demonstrate the links between… 

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References

SHOWING 1-10 OF 193 REFERENCES

Coral Resistance to Disease

TLDR
Predictive epidemiological models include not only terms for transmission of infectious microorganisms, but also terms for host resistance, which can determine the spread rate and impact of disease.

Insights into the anti‐microbial defense of marine invertebrates: the penaeid shrimps and the oyster Crassostrea gigas

TLDR
Genomics and gene profiling are promising to deepen the understanding of the anti‐microbial defense of the oyster and the shrimp, but real progress will depend also on the characterization of hemocyte lineages and hematopoiesis of these marine invertebrates as well as on the ontogenesis of their immune systems.

The Elusive Baseline of Marine Disease: Are Diseases in Ocean Ecosystems Increasing?

TLDR
A proxy to evaluate a prediction of the increasing disease hypothesis: the proportion of scientific publications reporting disease increased in recent decades is developed, the first quantitative use of normalized trends in the literature to investigate an ecological hypothesis.

The rising tide of ocean diseases: unsolved problems and research priorities

TLDR
Five major unsolved problems and priorities for future research for managing disease in the world's oceans are identified: detecting origins and reservoirs for marine diseases and tracing the flow of some new pathogens from land to sea.

Shrimp immunity and disease control

Climate Warming and Disease Risks for Terrestrial and Marine Biota

TLDR
To improve the ability to predict epidemics in wild populations, it will be necessary to separate the independent and interactive effects of multiple climate drivers on disease impact.

Evidence for a direct link between stress and immunity in the mollusc Haliotis tuberculata.

TLDR
Results indicate that in the abalone H. tuberculata, as in vertebrates, a link exists between stress and the immune system, which may begin to answer why stress and disease outbreaks are linked in shellfish.

Immunotoxicity in Invertebrates: Measurement and Ecotoxicological Relevance

TLDR
An integrated approach for the use of immunological biomarkers in environment management is proposed, combining measures of immune function and organismal viability at the biochemical, cellular and population level.

Physiology of Immunity in the Water Flea Daphnia magna: Environmental and Genetic Aspects of Phenoloxidase Activity

TLDR
The results suggest adaptive variation in PO activity and suggest that its expression is costly, which may influence the evolution of the PO activity level and the maintenance of its genotypic variation.
...