Innate Immunity, Environmental Drivers, and Disease Ecology of Marine and Freshwater Invertebrates

  title={Innate Immunity, Environmental Drivers, and Disease Ecology of Marine and Freshwater Invertebrates},
  author={Laura Mydlarz and Laura E. Jones and C. Drew Harvell},
  journal={Annual Review of Ecology, Evolution, and Systematics},
Despite progress in the past decade, researchers struggle to evaluate the hypothesis that environmental conditions compromise immunity and facilitate new disease outbreaks. In this chapter, we review known immunological mechanisms for selected phyla and find that there are critical response pathways common to all invertebrates. These include the prophenoloxidase pathway, wandering phagocytic cells, cytotoxic effector responses, and antimicrobial compounds. To demonstrate the links between… 

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